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KMID : 1134120070100020162
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Journal of Breast Cancer
2007 Volume.10 No. 2 p.162 ~ p.168
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Introduction of Electrochemical Therapy (EChT) and Application of EChT to The Breast Tumor
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Yoon Dae-Sung
Ra Yu-Mi
Ko Dae-Gyoung
Kim Yoon-Mee
Kim Keum-Won
Lee Hoi-Young
Xin Yu-Ling
Zhang Wei
Li Zing-Hong
Kwon Hee-Uk
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Abstract
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Purpose: To introduce the history and principle mechanism of electrochemical treatment (EChT) with animal study and report two cases successfully treated breast cancer and hemangioma by EChT.
Methods: In animal study, the breast cancer tumor in nude mouse treated with EChT (100 Coulomb/cm3) were reviewed for histologic changes. In the case studies, we reported method of EChT and clinical results after EChT. Case 1: 74 yr old female with locally advanced breast cancer received 3 times EChT with 1,000 Coulomb/time, 8 Volt. Case 2: 51 yr old female with breast hemagioma received one time EChT with 80 Coulomb, 8 Volt.
Results: In animal study, There were destructive change including vaculated cell fragment and extensive coagulative necrosis. Case 1 showed no local recurrence during 18 monthes after EChT. Case 2 also showed no evidence of recurrence of hemangioma.
Conclusion: The EChT is easy to use. It is effective, safe, less traumatic and makes patients recover quickly. This is a new and effective method to treat patients with tumours that are inoperable and can not receive chemotherapy or radiotherapy.
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KEYWORD
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Electrochemical therapy, Breast cancer, Hemangioma
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